MSC Therapy – Mesenchymal Stem Cells

admin Sty 06, 2016

MSCs are immunomodulatory, multipotent and fast proliferating and these unique capabilities mean they can be used for a wide range of treatments.
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Stem Cells have different properties:

  1. 
Cellular Differentiation
    These cells can differentiate into neural cells, bone, cartilage, hepatic and renal cells and can build new blood vessels, thus, help in regenerating the diseased or injured tissues.
  2. Immune System Regulation
    MSCs possess strong anti-inflammatory and immuno-modulatory properties. These cells regulate the immune system and reduce inflammation which helps in treating autoimmune and other inflammatory conditions. Specifically, MSCs increase activity of T cells, B cells, natural killer cells and dendritic cells.
  3. Cell Communication and Signaling Effects
    MSCs secrete a broad variety of cytokines, chemokines, and growth factors which help these cells in honing to the injury site. They then stimulate the existing stem cells and promote cell differentiation.

 

Sources of hematopoietic stem cells

There are three, now commonly used in medicine, KKM sources: bone marrow, peripheral blood and umbilical cord blood.

Wharton mesenchymal stem cells are an advanced therapy medicinal product (ATMP).

The manufacture of the medicinal product takes place in the Laboratory of Cell Engineering of the Polish Bank of Stem Cells S.A. On the basis of the approval of the Chief Pharmaceutical Inspector.

In November of 2014, the first mesenchymal cells were administered to our patients with amyotrophic lateral sclerosis and autism.

Stem cell therapy is available as a medical experiment that delays the onset of disease by helping to regenerate damaged neurons, which can alleviate symptoms in a patient.

Mesenchymal stem cells have immunosuppressive and immunomodulating effects.

Indications treated curently

Neurological:

  • ALS
  • SM
  • Muscular dystrophies
  • Ataxia
  • Autism
  • Spinal muscular atrophy

Ophthalmical

  • Optic neuropathy
  • Atrophy of the optic nerve
  • Stargardt’s disease
  • Behcet’s disease
  • Retinitis pigmentosa
  • Hypoplasia of the optic nerve

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